Description Of Drugs Related To Povidone-iodine Compounds

Ingredients
This product contains 0.05g of the main ingredient povidone-iodine per ml. Excipients: disodium hydrogen phosphate, sodium dihydrogen phosphate, potassium iodate, purified water.
category
Chemical drugs and biological products >> Surgical drugs and antiseptic drugs
Chemical drugs and biological products >> Dental drugs [2]
Traits
This product is reddish brown liquid.
Features
1. Compound PVP-Ⅰ is a new type of highly efficient disinfectant and antiseptic. A 0.7% to 10% solution can release 1.8 to 24 ppm of free iodine in water, killing microorganisms through the oxidation of the latter. The killing effect of bacteria is better than that of Xianbitai, and it has certain lethality to bacterial spores. The drug has significant killing effect on Candida albicans, Staphylococcus aureus, Escherichia coli, Bacillus subtilis, etc.; the sterilization time of Pseudomonas aeruginosa and Candida albicans is similar to that of compound iodine solution and iodine tincture of the same concentration, but its toxicity It is only 1/4~1/9. Compound PVP-Ⅰ has no toxic side effects, is low-priced, has a protective function for mucous membranes and skin, and its anti-STD effect is significantly better than Jieyin and potassium permanganate aqueous solutions.
2. Gradually release iodine in the solvent, which plays a slow-release role to maintain the bactericidal power for a longer period of time. Its powerful bactericidal mechanism is to oxidize the active groups of the protoplasmic proteins of pathogens and combine with the amino groups of proteins to denature them, thereby effectively killing pathogens such as bacteria, spores, fungi, viruses and protozoa. It has the characteristics of strong bactericidal power, wide sterilizing range, minimal irritation, light yellowing, easy cleaning, and no allergic reaction.
3. It has a rapid killing effect on hundreds of bacteria and viruses such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Candida albicans, etc. This product is currently the first choice disinfectant and antiseptic for direct use on human skin and mucous membranes at home and abroad.
4. It works due to the gradual decomposition of free iodine. Among them, 80%-90% of the bound iodine can be depolymerized into free iodine, which can directly denature and precipitate the proteins in the pathogen, causing the death of the pathogen cells, thereby achieving the purpose of efficient disinfection and sterilization. It is characterized by strong bactericidal power, low toxicity, and is a broad-spectrum bactericide that can kill viruses, bacteria, spores, fungi and protozoa. It has a strong killing effect on Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Treponema pallidum, Hepatitis B virus, HIV, Trichomonas vaginalis, etc.
5. External use can cause skin allergic reactions and be irritating to the skin and mucous membranes. Use on severely burned or large-area peeled skin can cause systemic adverse reactions, such as metabolic acidosis, hypernatremia and renal function damage. People who are allergic to iodine or have burns with an area greater than 20% should not apply it locally. It is not suitable for patients with toxic colloid thyroid tumors. Pregnant women and newborns should be cautious when using it in large areas. Not recommended for children under 4 years old.
6. It has a wide bactericidal spectrum and strong bactericidal power, and can directly kill bacteria, fungi, viruses, spores and protozoa. The sterilization speed is fast, most bacteria can be killed within 30 seconds, and 5 minutes is enough to kill individual bacteria. It is non-irritating to skin and mucous membranes and can be used for disinfection and treatment of body cavities, mucous membranes and ulcer surfaces. Non-toxic. It is not easy for microorganisms to develop drug resistance and allergic reactions. Durable use, good stability, long storage validity period. Easily soluble in water, easy to clean, and does not pollute or damage fabrics and other items.
7. This product is a high-efficiency gynecological sterilizing and disinfecting product. Its pH value is similar to that of the vagina and is mild. After dilution (warm water) according to the instructions, it can reach 300ppm effective iodine, which is 10-20 times more than the sterilizing concentration. It can be effectively killed after washing. various pathogenic microorganisms.
Pharmacological effects:
Povidone-iodine is an iodophor disinfectant that can directly denature and precipitate proteins in bacteria, causing the death of pathogenic microorganisms, thereby effectively disinfecting and sterilizing viruses, bacteria, spores, fungi, protozoa, etc., and has low toxicity. Povidone-iodine aqueous solution has strong pharmacological activity against Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Treponema pallidum, hepatitis B virus, HIV, Trichomonas vaginalis, etc.
Povidone-iodine gel is a semi-fluid colloid for gynecological external use made of povidone-iodine and a hydrophilic matrix. It is a system that maintains its sustained release. Due to the continuous release of free iodine, the skin and mucous membranes maintain a certain iodine concentration, inhibiting and killing bacteria. It is mainly used for gynecological vaginal infections. It is miscible with vaginal secretions, kills pathogenic microorganisms in secretions, blocks the spread and invasion of sexually transmitted diseases, and treats other bacterial infections of vaginal diseases.