Crospovidone Pubchem25249-54-1

Crospovidone Pubchem25249-54-1

Crospovidone is a synthetic polymer used as a disintegrant, binder and diluent in the pharmaceutical industry. It is a crosslinked PVP polymer that rapidly absorbs water, swells, and disintegrates to help release the drug quickly.
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Product Introduction
Product description

 

Crospovidone is a synthetic polymer used as a disintegrant, binder and diluent in the pharmaceutical industry. It is a crosslinked PVP polymer that rapidly absorbs water, swells, and disintegrates to help release the drug quickly. Crospovidone PubChem is a database that contains information about this substance, including chemical and physical properties, safety data, and links to scientific articles. It is a valuable resource for researchers and manufacturers in the pharmaceutical industry.

Product name :PVPP cross-linked povidone

Chemical Name:Crosslinked polymer

CTFA name:Crosslinked Polyvinylpyrrolidone

CAS No.:25249-54-1

Storage:Keep away from light, seal, and store in a dark place.

Package:20kg/cardboard drum

 

Physical properties:

 

This product is white or almost white powder; it is almost odorless; it is hygroscopic. This product is insoluble in water, ethanol, chloroform or ether. This product has high capillary/water content, large specific surface, strong hydration capacity (HK: 5.6), high and rapid water absorption (58.5%), strong water swelling capacity, swelling coefficient of 2.25-2.30, and polyethylene Pyrrolidone has the same complexing ability and can complex a variety of substances, such as phenols and iodine.

 

Application:

 

This product is white or colorless powder, odorless or slightly characteristic odor, basically tasteless, insoluble in water, alkali, acid and organic solvents. It has hygroscopicity and water absorption. It dissolves and swells after absorbing water, but does not form a gel; after absorbing water, the molecular chain stretches and the volume increases rapidly, and the expansion pressure can cause the tablet to disintegrate rapidly.

Due to the high molecular weight and cross-linked structure of cross-linked povidone, it is insoluble in water but can quickly promote the expansion of its network structure and disintegrate when exposed to water, and is widely used as a disintegrant for tablets in medicine, and is widely used as a suspension stabilizer, a complexing agent for pharmaceutical ingredients, and a complexing agent for tannins and polyphenols in plant drugs

 

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