Povidone Powder Chemicals9003-39-8
INCI/CTFA Name: PVP (Polyvinylpyrrolidone)
CAS Number: 9003-39-8
Basic Info:
Pharmacopoeia Name: PovidoneChemical Name: Polyvinylpyrrolidone
INCI/CTFA Name: PVP (Polyvinylpyrrolidone)
CAS Number: 9003-39-8
.
Properties: powder or aqueous solution, soluble in water, alcohol, amine and halogenated hydrocarbons, insoluble in acetone, ether, etc. It has excellent solubility, biosolubility, physiological inertness, film-forming, membrane body protection ability and the ability to compound a variety of organic and inorganic compounds, and is relatively stable to acids, salts and heat, so it has a wide range of uses.
Application: Povidone has a wide range of applications in the field of medicine, and is one of the three major new pharmaceutical excipients advocated by the world. The most widely used are adhesives for tablets and granules. It can also be used as a grafting agent for capsules, a detoxifier and lubricant for eye medicine, a co-solvent for injections, a dispersant for liquid preparations, and a stabilizer for enzymes and heat-sensitive drugs. Povidone can also be combined with iodine to synthesize povidone-iodine (PVP-I) disinfectant and fungicide. In contact lenses, PVP is used as an ingredient in contact lenses to increase their hydrophilicity. PVP can also be used as a cryopreservation agent in medicine.
|
Parameter |
Specification |
|
CAS No |
9003-39-8 |
|
Particle Size |
90% <100μm |
|
Residual NVP |
≤100 ppm (HPLC) |
|
Bulk Density |
0.35–0.55 g/cm³ |
|
Loss on Drying |
≤5.0% |
Industrial Applications
Tablet binding: Wet/dry granulation binder
Inkjet inks: Pigment dispersant
Detergents: Anti-redeposition polymer
Ceramics: Binder for spray-dried granules
Adhesives: Remoistenable glue base
Processing Protocol
Solution Prep: Hydrate in cold water
01
Direct Compression:** 2–5% w/w tablet blends
02
Incompatibilities: Avoid strong oxidizers/peroxides
03
Gelation Risk: Solutions >25% w/v unstable
04
Material Performance
Tablet Hardness: 100–150 N (K30, 5% w/w)
Ink Viscosity: 8–12 cPs (K15 @ 10%)
Detergent Efficacy: 30% soil redeposition reduction
Ceramic Green Strength: ≥15 MPa
Supply Specifications
Packaging
25kg PE-lined drums (nitrogen flushed)
Grades
Pharma (USP), Industrial (low metals)
Quality
Batch-specific K-value/GC reports
Regulatory
DMF Type IV (#DMF 35462)
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