Povidone Usp 43 9003-39-8

Medicine & Health

Povidone usp 43 has excellent physiological inertia, does not participate in human metabolism, and has excellent biocompatibility, and does not cause any irritation to skin, mucous membranes, eyes, etc. Pharmaceutical-grade PVP is one of the three new pharmaceutical excipients advocated internationally. It can be used as a binder for tablets and granules, a cosolvent for injections, and a glidant for capsules; detoxifiers, prolonged effects, and lubricating agents for eye drops It can also be used as a low-temperature preservation agent, as a dispersant for liquid preparations and stabilizers for enzymes and heat-sensitive drugs. Used in contact lenses to increase their hydrophilicity and lubricity. PVP K30 has been officially listed on the market with the approval of the national pharmaceutical management department. The company also supplies povidone K30 with approval number.

From a biological point of view, the molecular structure of PVP is similar to that of a simple protein model, and even its water-soluble ability to cooperate with certain small molecules and can be used by certain protein precipitants, ammonium sulfate, The properties of trichloroacetic acid, tannic acid and phenols are also compatible with protein. As a result, PVP is widely used as an excipient for pharmaceutical preparations, and its specific applications are as follows: ①Used as a binder for preparations ②Co-precipitating agent ③Used as a co-solvent or crystal formation inhibitor in injections ⑤Controlled release of retarder and sustained-release drug can prolong the action time of the drug. ⑥ Artificial vitreous and cornea ⑦ Surgical bandage ⑧ PVP iodine disinfectant. In addition, PVP can also be used as a coloring agent and X-ray contrast agent; it can be used in a variety of dosage forms such as tablets, granules, liquids, etc. It has the effects of detoxification, hemostasis, increasing the dissolved concentration, preventing peritoneal adhesions, and promoting erythrocyte sedimentation rate.

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