Introduction and functions of disintegrants

Disintegrating agents refer to substances that can quickly break tablets into small particles in gastrointestinal fluid, so that functional ingredients can be quickly dissolved and absorbed to play their role. Most of these substances have good water absorption and swelling properties, thereby achieving tablet disintegration. Except for sustained-release tablets and some special-purpose tablets, disintegrants should be added to general tablets.
The role of disintegrants
The purpose of a disintegrant is to break up the binding forces created by binders or high compression, causing the tablet to disintegrate in water. Tablet disintegration undergoes wetting, siphoning, and fragmentation.