Povidone VA64 Copovidone

Product Name: Povidone VA64 Copovidone
USP/EP Name: Copovidone, Copovidonum
INCI: VP/VA copolymer 60/40
CAS NO.: 25086-89-9
Appearance: White to light yellow free-flowing powder with good fluidity, odorless or slightly characteristic odor;
Main Properties: Less hygroscopic than Povidone K30, soluble in organic solvents such as water and ethanol, lower glass transition temperature than Povidone K30, and capable of forming a transparent water-soluble film;
Product Standards: Compliant with USP3/NF, EP, BP, JPE

As a binder suitable for wet and dry granulation processes of tablets and direct powder compression processes to improve particle compressibility;

As a coating film-forming agent for film coating of tablets;

As a pore-forming agent in taste-masking formulations and sustained-release preparations;

As a solubilizer in solid dispersion processes, etc.

Strong plasticity, capable of imparting good hardness to tablets, and an excellent dry binder for direct compression processes;

Suitable for drugs with poor compressibility, improving drug compressibility to meet direct compression process requirements;

An excellent binder for preparing effervescent tablets and dispersible tablets;

Used in combination with HPMC/HPC/PVA, etc., effectively improving film elasticity and adhesion to the tablet core, enhancing the gloss of the coating film, reducing HPMC viscosity, improving the plasticity of the cellulose film, reducing film brittleness, and reducing the amount of plasticizer used;

Suitable for primer layers of plain tablets, taste-masking formulation recipes, and pore-forming agents for sustained-release coating films;

With good plasticity, suitable for preparing drug solid dispersions by hot-melt extrusion;

Capable of forming polymer complexes with drug molecules in water through hydrogen bonding, used as a skeleton material for gastric retention tablets with good retention performance, prolonging drug release time, improving drug absorption, and enhancing bioavailability.

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