Pvpp Sigma 9003-39-8

white or milky white free-flowing powder, easy to absorb moisture, odorless or slightly odorous, insoluble in water, alkali, acid and commonly used organic solvents, with strong swelling performance and complexation ability with many types of substances.

Storage: The finished product should be sealed and stored in a cool and dry place.

Manufacturer: ISP (International Specialty Products) Company, BASF (BASF) Company, etc.

Application example: There are many examples of cross-linked polyvinylpyrrolidone used as a tablet disintegrant. About 20% of tablet varieties are using it. Because cross-linked polyvinylpyrrolidone is slightly more expensive than ordinary disintegrants such as general starch and sodium carboxymethyl starch, it is generally used in higher-end tablet varieties.

Azithromycin dispersible tablets

Take azithromycin 14.25KG, saccharin sodium 0.17KG, povidone 0.25KG, hydroxypropyl cellulose 1.71KG, microcrystalline cellulose 4.25KG and lactose 1.0KG, mix well, add 2250ml ethanol to make a soft material, granulate through a 40-mesh sieve, dry at 75°C for 2 hours, sieve through a 40-mesh sieve, add 0.75KG sodium carboxymethyl starch, 0.87KG magnesium stearate, and cross-linked polyvinylpyrrolidone 1.0KG, mix well, and press into tablets. The tablets have good uniformity, dissolution, appearance and hardness.

Propranolol tablets

Propranolol 900mg, dextrin 277.0mg, cross-linked polyvinylpyrrolidone 50.0mg, micro-powder silica gel 0.9mg, magnesium stearate 2.1mg, tablets are obtained by direct tableting.

Ciprofloxacin hydrochloride tablets

Ciprofloxacin hydrochloride 50.0KG, instant sorbitol 150.0KG, cross-linked polyvinylpyrrolidone 30.0KG, microcrystalline cellulose 17.0KG, micro-powder silica gel 1.0KG, magnesium stearate 2.0KG, tablets are obtained by direct tableting.

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