
Iodine Swabs 25655-41-8
Pharmacopoeia Name: Povidone-iodine
Chemical Name: Polyvinylpyrrolidone complexes with iodine
INCI/CTFA Name: PVP-Iodine
CAS Number: 25655-41-8
Drug analysis
Basic information Chinese name: Povidone-iodine
English name: Povidone-iodine
Chemical formula: (C6H9NO)n·xI
CAS number: 25655-41-8
Physical and chemical properties Melting point: 300ºC
Flashpoint: 93.9ºC
Vapor pressure: 0.132mmHg at 25°C
Appearance: Yellow-brown to brown-red amorphous powder
Solubility: Soluble in water or ethanol, insoluble in ether or chloroform.
Main active ingredient: Complex of 1-vinyl-2-pyrrolidone homopolymer and iodine. Calculated on a dry basis, the effective iodine (I) content should be 9.0% to 12.0%. Properties Yellow-brown to reddish-brown amorphous powder. Soluble in water or ethanol, insoluble in ether or chloroform.
Identification Take about 0.5g of this product, dissolve it in 5mL of water, and test it according to the following method. (1) Take 1 drop of solution, add 9ml of water and 1ml of starch indicator solution, and a dark blue color will appear. (2) Take 0.5ml of the solution, apply it on a glass plate with an area of about 7.5cm×2.6cm, and place it at low humidity room temperature overnight to dry, forming a brown, dry film that is easily soluble in water. Check the loss on drying Take about 5g of this product, accurately weigh it, dry it at 105℃ for 4 hours, weigh it, and weigh it after drying for 1 hour each time, until the weight difference after two consecutive dryings does not exceed 5.0mg; the weight loss shall not exceed 8.0%.
Residue on ignition: Take 1.0g of this product and check it according to the law. The residue left shall not exceed 0.1%.
Heavy metals: Take the residue left under the residue on the ignition item and check it according to the law. The heavy metal content shall not exceed 20 parts per million.



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